23. Tucson, AZ

A lack of high-paying jobs and a poverty rate that's 66% higher than the national average means it's hard to make a living here. Add in the extremely hot temperatures in the summer and a dwindling water supply, and you'll understand why Tucson is a less-than-ideal place to live. Daily gridlock on the city's one main freeway, along with 40-minute commute times, make it even less desirable.
Unemployment rate: 4.3%
Median household income: $45,227
Walk Score ranking: 43 (car dependent)
24. Jackson, MS

Life in Jackson is tough, and one of the first things locals will tell you is to avoid going out at night. Jackson frequently makes the list as one of the most dangerous cities in the country. Crime rates here exceed both state and federal averages. The city's water treatment facility failed over the summer after years of neglect, leaving residents high and dry.
Unemployment rate: 4.3%
Median household income: $40,064
Walk Score ranking: 43 (car dependent)
